Improve Ion Throughput

High-Efficiency Ion Transport and Selection

Improve transmission, stability, and selectivity with RF ion guides, ion funnels, quadrupole mass filters, and tuned RF networks proven in demanding instruments.

Home / Applications / High-Efficiency Ion Transport and Selection

How Researchers Use Our Products

How Researchers Use Ardara

Explore the instrument challenge, the Ardara solution selected, and the performance reported by each research team.

Used by researchers 2009

Stanford University

Desorption Electrospray Ionization: Achieving Rapid Sampling Rates

Solution used
PSRF-100 radio-frequency power supply; two RF-only quadrupole ion guides

The Stanford team used an Ardara PSRF-100 supply to drive two RF-only quadrupole guides at 1.46 MHz in a rapid desorption electrospray ionization sampling system. The guides transported ions through a configuration designed to reduce carryover between sequential samples. The instrument resolved alternating analytes at up to 80 samples per second and a single analyte at 50 samples per second. This paper is an early public example of an Ardara RF supply supporting high-speed ambient ionization and automated sample throughput.

Published by Barbula et al. in Analytical Chemistry (2009).

Used by researchers 2009

Iowa State University

An Ion Trap-Ion Mobility-Time of Flight Mass Spectrometer with Three Ion Sources for Ion/Ion Reactions

Solution used
PSRF-100 radio-frequency power supply; ion funnel

An Ardara PSRF-100 supplied approximately 90 Vpp at 360 kHz to the instrument's ion funnel. The funnel coupled three ion sources to a hybrid ion trap-ion mobility-time of flight platform used for ion/ion reaction studies. The authors reported that the funnel increased total ion signal by roughly sevenfold. Ardara's role was therefore central to ion transmission and sensitivity rather than to a peripheral accessory. The paper also acknowledged Randy Pedder for technical advice, but it did not include an Ardara-affiliated coauthor and is classified here as an independent use.

Published by Zhao et al. in Journal of the American Society for Mass Spectrometry (2009).

Used by researchers 2012

University of California, Berkeley and Lawrence Berkeley National Laboratory

Slow Photoelectron Velocity-Map Imaging Spectroscopy of Cold Negative Ions

Solution used
Multiple radio-frequency supplies for hexapole, quadrupole, and octupole ion optics

The cryogenic photoelectron imaging instrument used Ardara RF supplies at several stages: a hexapole guide operated near 3 MHz and 200 Vpp, a quadrupole stage near 1.15 MHz, and an octupole trap with RF amplitudes up to 500 Vpp. These stages guided and trapped cold negative ions before velocity-map imaging. The completed system produced ion temperatures of 10 +/- 2 K and spectral peak widths as narrow as 4 inverse centimeters. This is a strong example of Ardara supplies coordinating multiple ion-optical elements in a precision spectroscopy instrument.

Published by Hock et al. in Review of Scientific Instruments (2012).

Used by researchers 2015

National High Magnetic Field Laboratory and Florida State University

21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometer: A National Resource for Ultrahigh Resolution Mass Analysis

Solution used
Tuned tank circuits for five injection quadrupoles

Five ion-injection quadrupoles in the 21 T FT-ICR platform were driven through Ardara-tuned tank circuits operating from approximately 2.7 to 3.9 MHz and up to 400 Vpp. The resulting national user instrument delivered more than two million resolving power for bovine serum albumin, mass accuracy below 150 parts per billion, and 68 percent sequence coverage for carbonic anhydrase using combined dissociation methods. Ardara hardware supported the demanding ion-transfer path of a flagship ultrahigh-resolution mass spectrometer.

Published by Hendrickson et al. in Journal of the American Society for Mass Spectrometry (2015).

Used by researchers 2017

University of California, Berkeley

Mass, Mobility and MSn Measurements of Single Ions Using Charge Detection Mass Spectrometry

Solution used
Two RF-only quadrupole ion guides; energy-selective electrostatic turning quadrupole

The Berkeley charge-detection mass spectrometer incorporated a pair of Ardara RF-only quadrupole guides and an energy-selective electrostatic turning quadrupole. Together, these elements enabled repeated manipulation and measurement of individual highly charged ions. The authors demonstrated MS7 analysis of a single multiply charged, approximately 8 MDa polyethylene glycol ion and reported about one percent energy precision. The work illustrates how Ardara ion optics can support single-particle experiments that require controlled recirculation, selection, and low-loss transport.

Published by Elliott et al. in Analyst (2017).

Used by researchers 2018

University of Florida

Operation and Performance of a Mass-Selective Cryogenic Linear Ion Trap

Solution used
Quadrupole mass filter upstream of a cryogenic linear ion trap

An Ardara quadrupole mass filter provided initial mass selection before ions entered a cryogenic linear ion trap. The platform produced reproducible spectra from 17 to 295 K and used stored-waveform inverse Fourier transform isolation to select fragile, nitrogen-tagged ions for background-free infrared spectroscopy. This use case connects Ardara mass-selection hardware with low-temperature ion chemistry and action spectroscopy, where clean precursor selection and stable transmission directly affect spectral quality.

Published by Tesler et al. in Journal of the American Society for Mass Spectrometry (2018).

Used by researchers 2021

Korea Advanced Institute of Science and Technology

Observation of the Ponderomotive Effect in Non-Valence Bound States of Polyatomic Molecular Anions

Solution used
RF generators for hexapole and octopole ion guides

Ardara RF generators powered the hexapole and octopole guides used to transport and prepare molecular anions for photodetachment spectroscopy. The authors reported the first experimental demonstration of the ponderomotive effect in non-valence-bound states of polyatomic molecular anions. The case is notable because the Ardara RF hardware supported a fundamental molecular-physics measurement in which stable ion guidance and well-controlled fields were prerequisites for observing a subtle light-matter interaction.

Published by Kang et al. in Nature Communications (2021).

Used by researchers 2023

Korea Advanced Institute of Science and Technology

Excited-State Chemistry of the Nitromethane Anion Mediated by the Dipole-Bound States Revealed by Photofragment Action Spectroscopy

Solution used
Radio-frequency quadrupole mass filter for initial mass selection

The experiment used an Ardara RF quadrupole mass filter to isolate nitromethane anions before transfer into a 25 K ion trap for photofragment action spectroscopy. The authors reported the first experimental observation of an excited dipole-bound state of the nitromethane anion and mapped its role in the excited-state reaction pathway. The Ardara filter provided the clean precursor population needed to assign weak, state-specific photochemical features with confidence.

Published by An et al. in Chemical Science (2023).

Plan Your Instrument with Ardara

Share your pressure regime, target mass range, RF or DC requirements, geometry, and control constraints. Our team can help match catalog components to your design or define a custom subsystem.