Used by researchers
2015
National High Magnetic Field Laboratory and Florida State University
21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometer: A National Resource for Ultrahigh Resolution Mass Analysis
- Solution used
- Tuned tank circuits for five injection quadrupoles
Five ion-injection quadrupoles in the 21 T FT-ICR platform were driven through Ardara-tuned tank circuits operating from approximately 2.7 to 3.9 MHz and up to 400 Vpp. The resulting national user instrument delivered more than two million resolving power for bovine serum albumin, mass accuracy below 150 parts per billion, and 68 percent sequence coverage for carbonic anhydrase using combined dissociation methods. Ardara hardware supported the demanding ion-transfer path of a flagship ultrahigh-resolution mass spectrometer.
Published by Hendrickson et al. in Journal of the American Society for Mass Spectrometry (2015).
Used by researchers
2019
The Ohio State University
Relative Interfacial Cleavage Energetics of Protein Complexes Revealed by Surface Collisions
- Solution used
- External multichannel power supply controlling ten surface-induced dissociation lenses
An external Ardara supply controlled ten DC lenses in a surface-induced dissociation device used to interrogate protein-complex interfaces. By varying collision conditions, the team showed that low-energy surface collisions preferentially cleave the weakest interfaces and developed a predictive model using structural interface features. The Ardara supply enabled coordinated control of the SID ion optics, supporting a workflow that linked gas-phase fragmentation patterns to native protein topology and assembly.
Published by Harvey et al. in Proceedings of the National Academy of Sciences (2019).
Used by researchers
2022
FELIX Laboratory, University of Amsterdam, and Radboud University
Gas-Phase Spectroscopy of Photostable PAH Ions from the Mid- to Far-Infrared
- Solution used
- Electron-impact ionizer for forming radical cations
An Ardara electron-impact ionizer generated radical cations of phenanthrene, pyrene, and perylene for infrared multiple-photon dissociation measurements in a 7 T FT-ICR mass spectrometer. Spectra covering approximately 100 to 1700 inverse centimeters were compared with the NASA Ames PAH database and theoretical predictions. The work demonstrates an Ardara ion source contributing to laboratory astrophysics: producing well-defined polycyclic aromatic hydrocarbon ions needed to interpret unidentified astronomical infrared emission features.
Published by Wiersma et al. in Monthly Notices of the Royal Astronomical Society (2022).
Used by researchers
2026
University of Wisconsin-Madison, Cal Poly, and Bradley University
A Chemical Ionization Residual Gas Analyzer for the Sensitive Detection of Atmospheric Trace Gases
- Solution used
- Multichannel DC supply for ion optics, digitally controlled through a DAQ
A multichannel Ardara DC supply powered the ion optics in a compact chemical-ionization residual gas analyzer and was digitally controlled through a National Instruments DAQ. The field-deployable instrument was built for less than $50,000, achieved a 20-second, 3-sigma detection limit of 18 ppt for deuterated dimethyl sulfide, and completed three days of ambient sampling. This case broadens the public application record from laboratory mass spectrometry to lower-cost atmospheric trace-gas monitoring.
Published by Wokosin et al. in Journal of the American Society for Mass Spectrometry (2026).
Co-developed with Ardara
2023
University of California, Berkeley and Ardara Technologies
Accurate Sizing of Nanoparticles Using a High-Throughput Charge Detection Mass Spectrometer without Energy Selection
- Solution used
- +/-4 kV electrospray supply, Broad-Head RF supplies, thin gate valve, three rectilinear quadrupole guides, and asymptotic electrodes
This high-throughput charge-detection instrument incorporated an unusually broad set of Ardara subsystems spanning ionization, RF transport, gating, and electrostatic optics. Nanoparticle size distributions agreed with transmission electron microscopy while measurements were completed up to roughly 80 times faster, including samples diluted about 50-fold; the instrument also resolved particle dimers. The coauthored paper is a clear public example of Ardara contributing to an integrated platform rather than a single replaceable component.
Published by Harper et al.; Randall E. Pedder was an Ardara-affiliated coauthor in ACS Nano (2023).
Co-developed with Ardara
2024
Massachusetts Institute of Technology and Ardara Technologies
Low-Cost, Compact Quadrupole Mass Filters with Unity Mass Resolution via Ceramic Resin Vat Photopolymerization
- Solution used
- Slim-Line ionizer, continuous-dynode electron multiplier, and preamplifier
The MIT-Ardara collaboration evaluated additively manufactured ceramic quadrupole mass filters using an Ardara Slim-Line source and Ardara detection electronics. The printed filter resolved a 131 Da peak with 0.50 Da full width at half maximum, corresponding to about 260 resolving power, while covering a 250 Da mass range and reaching 0.13 mA/Torr sensitivity. The paper demonstrates Ardara equipment enabling reproducible validation of a lower-cost manufacturing route for compact mass analyzers.
Published by Eckhoff et al.; Luke J. Metzler and Randall E. Pedder were Ardara-affiliated coauthors in Advanced Science (2024).